Jet lag – the disadvantage of having a clock in the modern world

Air travel challenges our bodies in a way that has never before been encountered in our evolutionary history. It allows us to move rapidly across multiple timezones, quicker than we could have ever moved by foot or animal. Unfortunately, our bodies are unable to adjust quickly enough. We are constrained by our circadian clocks, the things that give our bodies a sense of internal time, which have evolved to coordinate our physiology to the rhythmic and predictable changes in the external environment (as well as other roles) like day and night. The clock keeps its original time when you move timezones like a watch before you’ve reset it. It’s resistant to rapid change, giving us jet lag. However, unlike a watch, the body clock can gradually reset itself over a period of days so that we become tuned to a new local time. Despite this inbuilt mechanism, in an era of global travel it is often too slow.

Is it possible to speed up the resetting process? Can we travel the world without jetlag?

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Shifting your clock: shift work and the circadian clock

To many people, the phenomenon known scientifically as the circadian rhythm is bleeding obvious. We sleep in the night and are awake during the day, long-haul flights like those from the UK to Australia gives you jetlag, and night shifts are a right pain in the bum. Detailed explanations involving transcription-translation feedback loops and phase response curves don’t change those facts, they’re a fact of life when we live on a rotating world. But many scientists, myself included, are fascinated in the details, and some scientists, like Céline Vetter and colleagues at the Institute of Medical Psychology at Ludwig-Maximilian-University in Munich, use this eye for detail to find out how we might best cope with our biological timing in a 24-hour society.

Coffee: Are you an early bird or a night owl?

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