Rhythms in red blood cells and the ever-present casein kinase
My latest research was published in Journal of Biological Rhythms this week. It is open access here: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells.
What can a blind cavefish tell us about circadian clocks?
Circadian clocks and a revolving planet go hand-in-hand. But why so many plants and animals have a circadian clock from an evolutionary perspective is relatively unknown. One way to find out is to study animals that live in non-rhythmic environments. And at the end of 2013, my team published a study on exactly that: the…
Shifting your clock: shift work and the circadian clock
To many people, the phenomenon known scientifically as the circadian rhythm is bleeding obvious. We sleep in the night and are awake during the day, long-haul flights like those from the UK to Australia gives you jetlag, and night shifts are a right pain in the bum. Detailed explanations involving transcription-translation feedback loops and phase…
Why have a circadian clock?
Almost every animal and plant on the planet has a circadian clock, even those that live in the depths of the sea and deep underground in caves. The presence of clocks in almost all life-forms implies that it is a helpful or advantageous characteristic, an evolutionary adaptation, serving to improve the fitness of the organism. This…
How do you study circadian rhythms?
Science requires controlled and well-planned experiments. Without correct set-up, results from experiments may not be reliable enough to be trusted. Circadian biology is no different in that regard, and especially when trying to find out if something has a working circadian clock, controlled experiments are crucial.